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Steve Jobs on Leave with Pancreatic Cancer
1/18/2011 - Christine Traxler

Nearly two years since receiving a new liver and fighting a rare form of pancreatic cancer, Steve Jobs, the co-founder and chief executive of Apple Inc., announced to his employees Monday he will take an indefinite leave of absence from the company to focus on his health.

While Jobs did not address specific health reasons, many experts say it's likely that his leave is related to his ongoing treatment for pancreatic cancer.

Jobs, who was diagnosed with pancreatic cancer in 2004, initially underwent surgery to remove the tumor. A few months after announcing a leave of absence in January 2009, Jobs had a liver transplant.

Experts say the length of his survival is mainly because he had a slow-growing, rare cancer called a pancreatic neuroendocrine islet cell tumor. While experts say neuroendocrine cancers are known to spread to the liver, Jobs remained private about his condition and the reason behind his transplant.

"You hear the term pancreatic cancer and you immediately think Pavarotti or Patrick Swayze, but this is a completely different animal," Dr. Andrew Warshaw, surgeon-in-chief at Massachusetts General Hospital, said.

"For adenomas, the timeline is very short. The pace of progress with neuroendocrine cancers can be many years, even with metastatic disease. It has a different biology," said Warshaw.

Only 6 percent of patients with any form of pancreatic cancer live longer than five years, according to the nonprofit organization Pancreatic Cancer Action Network.

"There's a lot we need to learn about pancreatic cancer, but more so on the islet form," said Julie Fleshman, president and CEO of the Pancreatic Cancer Action Network.


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